Cohort study on Association of Stress and Cortisol level in Antenatal women with Developmental Effects in the off-spring

Common mental disorders such as depression and anxiety during pregnancy constitute an emerging public health problem and call for timely detection and intervention to prevent any adverse pregnancy outcome. Pregnancy is commonly associated with elevated levels of a stress related hormone known as ‘cortisol’. In our study we are screening pregnant women for the presence of depression and anxiety using validated measuring scales. We are also estimating cortisol level through a non-invasive saliva sample collection method during early, mid and late pregnancy.

This study aims to prospectively assess the association of maternal depression and anxiety during pregnancy along with her cortisol levels with the motor and cognitive development of the offspring using DASII scale (Developmental Assessment scale for Indian infants).